Mlb Season Schedule 2025. The 2025 season will begin in japan at the tokyo dome, with the dodgers and cubs squaring off in the tokyo series presented by guggenheim. The mlb regular season will begin on thursday, march 27, 2025, and runs through sunday, september 28, 2025.
The los angeles dodgers and shohei ohtani will open the 2025 season in tokyo against the chicago cubs on march 18 and the athletics will start the home portion of their first. Full schedule for the 2025 season including full list of matchups, dates and time, tv and ticket information.
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